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Cervical Cancer Vaccine

clinical trials have shown that HPV vaccines are highly effective in preventing cervical infection with the types of HPV they target when given before first exposure to the virus that is, before individuals begin to engage in sexual activity. HPV vaccines have also been found to reduce infections in other tissues that HPV infects, including the anus and oral region. Because the cell changes and cancers caused by HPV take years to develop, it has only recently been confirmed that the vaccines reduce the risk of these outcomes as well. Trials and real-world data from population-based studies have now demonstrated that the vaccines greatly reduce the risk of precancers and cancers of the cervix, vagina, and vulva in vaccinated women. A clinical trial of Gardasil in men indicated that it can prevent anal cell changes caused by persistent infection. The trials that led to the approval of Gardasil 9 found it to be nearly 100% effective in preventing cervical, vulvar, and vaginal infections and precancers caused by all seven cancer-causing HPV types that it targets.

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